1mng Tacrolimus Hard Capsules are an immunosuppressive medication used to prevent organ rejection in patients who have received organ transplants, such as kidney, liver, heart, or lung transplants. The drug is commonly sold under various brand names, including Prograf®, Advagraf®, and others. Tacrolimus is available in various formulations, including immediate-release hard capsules (Prograf®) and prolonged-release formulations (Advagraf®). The prolonged-release formulation provides a more consistent drug release and may require less frequent dosing compared to the immediate-release form. 1mng Tacrolimus Hard Capsules works by inhibiting the activity of certain immune cells known as T-lymphocytes or T-cells.